Allergic contact dermatitis and lip rashes may be due to flavorings in chapsticks, lip balms, toothpaste and food, preservatives in makeup, and other substances. A lipstick allergy can be difficult to diagnose in some cases as it is possible that cheilitis can develop without the person even wearing lipstick. Patch tests were positive to Zovirax cream, propylene glycol, the patient's favourite lipstick and propyl gallate. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 1997;124(4):315-7. Allergic contact cheilitis generally presents as eczema-like changes on the vermilion margin or skin around the mouth. Chronic sun exposure, such as occurs among people who work outdoors, can lead to inflammatory changes of the lower lip known as actinic or solar cheilitis, reports the New Zealand Dermatological Society on DermNet NZ 4. If you do not receive an email within 10 minutes, your email address may not be registered, Sometimes, having itchy lips is a symptom of other less common health conditions. Allergic contact cheilitis is a contact allergic reaction on lips. Concentration and vehicle adapted for for patch tests]. Most of the time, having itchy lips is related to a contact or seasonal allergy. 2008 Mar;58(3):178-9. doi: 10.1111/j.1600-0536.2007.01225.x. Multicentre study of allergic contact cheilitis from toothpastes. (Cheilitis is the medical word for “inflamed lips” and covers a broad range of causes and symptoms.) Dermatol Clin. It is also known as lipstick cheilitis since several ingredients found in lipsticks may act as irritants. 1996 Oct;51(10):755-6. doi: 10.1111/j.1398-9995.1996.tb02122.x. Contact cheilitis is a term used to describe inflammation of the lips, most often caused by either irritant contact cheilitis (ICC) or allergic contact cheilitis (ACC) (9). It is due to a type IV hypersensitivity reaction following contact with an allergen. Francalanci S, Sertoli A, Giorgini S, et al. Schena D, Fantuzzi F, Girolomoni G. Contact allergy in chronic eczematous lip dermatitis. If you have previously obtained access with your personal account, please log in. Irritant cheilitis often comes from lip licking, a constant source of irritation to the skin of the lips, and a … Enter your email address below and we will send you your username, If the address matches an existing account you will receive an email with instructions to retrieve your username, I have read and accept the Wiley Online Library Terms and Conditions of Use, https://doi.org/10.1111/j.1440-0960.2007.00380.x. Allergic contact cheilitis caused by carnauba wax in a lip balm. Whenever your skin barrier is impaired, you are at higher risk for allergic skin reactions. Allergic contact cheilitis is the term for itchy or inflamed lips caused by exposure to an allergen. No reaction was seen with Zovirax ophthalmic ointment and Zovirax tablet. The latter can be due to lip products, toothpaste, dental materials, medication or a combination of factors. The reaction may present in either acute or more persistent chronic forms. It looks like an eczema-type inflammation on the outer edge of the lips and is due to a type IV hypersensitivity reaction following contact with an allergen. Allergic contact cheilitis is allergic contact dermatitis affecting the lip (s). This can be further broken down into irritant contact cheilitis – which is often caused by lip licking, cosmetics, foods and environmental factors – and allergic contact cheilitis. Contact Dermatitis 2000; 43:216. Sometimes the reaction extends onto adjacent perioral skin, with or without the involvement of the angles of the mouth. OK, So Contact Dermatitis Can Strike The Lips, Too? Please check your email for instructions on resetting your password. Allergic contact dermatitis to Zovirax cream. Allergic contact cheilitis is more common in women than men. The propylene glycol component of the Zovirax® cream and the propyl gallate component of the lipstick were regarded as the responsible contact sensitizers. 1995 Oct;33(4):255-7. doi: 10.1111/j.1600-0536.1995.tb00477.x. Contact Dermatitis. NLM [Contact eczema induced by propylene glycol. Allergic contact cheilitis is more common in women than men. Similar to contact dermatitis are irritant cheilitis and allergic cheilitis. 2009 Jul;27(3):265-80, vi. Allergic contact cheilitis: A relevant allergic reaction is identified in one quarter, at least, of cases of lip eczema. Causes of cheilitis The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Patch tests were positive to Zovirax ® cream, propylene glycol, the patient's favourite lipstick and propyl gallate. Keep reading to find out what could be causing your lips to feel itchy. Allergic contact cheilitis affects more women than men and more adults than children, although it can affect all age groups. In the case of women, lip cosmetics ar… Allergic contact cheilitis is a chronic superficial inflammatory disorder of the vermilion borders characterized by desquamation due to delayed-type hypersensitivity reaction. Vaseline may help. This site needs JavaScript to work properly. Adolescent A 29‐year‐old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax ® cream. The differential diagnosis was challenging due to concomitant contact sensitization with these agents. Eczematous cheilitis (also known as contact cheilitis) is dryness, erythema, and/or fissuring of the lips secondary to an inflammatory response to allergens in contact with the lips. Allergic Contact Cheilitis Due to Lip Cosmetics Lipsticks and lipcare products are the commonest cause of allergic contact cheilitis in women. Eczematous cheilitis is the most common cause. It is due to a type IV hypersensitivity reaction following contact with an allergen. Allergic or irritant contact cheilitis is caused by a reaction to an irritant or allergen that touches the lips, such as: 2 Lipstick or lip balms Oral hygiene products, like toothpaste or mouthwash Fragrances (e.g., balsam of peru) 3 The changes may be fairly localised or affect the whole lip. and you may need to create a new Wiley Online Library account. Exogenous eczematous cheilitis is caused by factors outside the body. Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. (2)2 Division of Dermatology, University of Ottawa, Ottawa, ON, Canada. Granulomatous cheilitis is a condition that causes persistent swelling of the lips. Granulomatous cheilitis. Allergic contact cheilitis describes a not uncommon inflammatory reaction of the lips. Allergic contact cheilitis caused by ditrimethylolpropane triethylhexanoate in a lipstick Allergic contact cheilitis caused by ditrimethylolpropane triethylhexanoate in a lipstick Miura, Maiko; Isami, Mamiko; Yagami, Akiko; Matsunaga, Kayoko 2011-05-01 00:00:00 Lipsticks are composed of dyes, flavouring agents, sunscreens, vehicle components, and preservatives. Pastor N, Silvestre JF, Mataix J, Lucas A, Pérez M. Contact Dermatitis. Patch tests were positive to Zovirax® cream, propylene glycol, the patient's favourite lipstick and propyl gallate. It is due to a type IV hypersensitivity reaction following contact with an allergen. Working off-campus? Ann Dermatol Venereol. Zhou LL(1), Pratt M(2). A possible cause of cheilitis is contact allergy. Involvement of the angles of the mouth may also be seen (angular-cheilitis). A 29-year-old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax cream. Unlimited viewing of the article PDF and any associated supplements and figures. 19 Perioral Region “Lip licker dermatitis” is an irritant dermatitis that involves the perioral skin. USA.gov. Güzin Özarmağan, MD. In both situations, you may have rashes elsewhere on your body. The propylene glycol component of the Zovirax cream and the propyl gallate component of the lipstick were regarded as the responsible contact sensitizers. It's more common in women, probably because they are much more likely to wear lipstick, one of the most frequent causes of contact cheilitis. It is due to a type IV hypersensitivity reaction following contact with an allergen and usually presents as an eczema -like inflammation of the outer lip or vermilion margin. One or both lips may be red with dryness, scaling and cracking. Irritants include spices, artificial flavors, harsh soaps, toothpaste, moisturizers, lip balms, NIH 20-22 Clinically, there is usually a hyperpigmented circumferential symmetric plaque that is … Allergic contact dermatitis of the lips, also known as allergic contact cheilitis It doesn't matter whether it's your face, your arms, or your lips. Unlimited viewing of the article/chapter PDF and any associated supplements and figures. For some people, soap of any kind may be too harsh for the face and lips. Allergic contact cheilitis. More than lipstick alone can lead to contact cheilitis, though. No reaction was seen with Zovirax® ophthalmic ointment and Zovirax® tablet. Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. Esen Özkaya, MD. Allergic contact cheilitis caused by carnauba wax in a lip balm Contact Dermatitis. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. A 29-year-old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax cream. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. HHS Allergic contact cheilitis is a common cause inflammation of the outer lip or vermillion margin. We reviewed its allergic causes, and suspect that the literature does not adequately document the … Ophaswongse S, Maibach HI. Actinic cheilitis is a precancerous condition, which may lead to squamous cell carcinoma if left untreated. | The most common causes of allergic contact cheilitis is lip cosmetics, including lipsticks and lip balm, followed by toothpastes. There are many common sources of allergens including lipsticks and other lip-care products, toothpastes and dental materials, foods, medications and nail varnish. | And as the majority of patients providing with cheilitis are women, this makes these products the most common general source of allergens. Allergic Contact Cheilitis From a Variety of Lip Balm Ingredients. Your skin barrier works great in most cases. PMID: 29039219 [Indexed for MEDLINE] Publication Types: Case Reports; MeSH terms. No reaction was seen with Zovirax ® ophthalmic ointment and Zovirax ® tablet. Would you like email updates of new search results? Learn about our remote access options, Department of Dermatology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey. doi: 10.1016/j.det.2009.05.014. Bourezane Y, Girardin P, Aubin F, Vigan M, Adessi B, Humbert P, Laurent R. Allergy. Learn more. When contact dermatitis affects the lips, it's referred to as contact cheilitis. Lipsticks and other lip care products are the major causes of allergic contact cheilitis of the vermilion margin, where the skin and red lip meet. Lip cosmetics, sunscreens, toothpas… This may be due to skin diseases such as atopic dermatitis or by contact with allergic or irritant materials, or both. The lips may also itch or burn. Lip cosmetics are the most common allergen source in women, while toothpastes allergy occur mostly in men. Use the link below to share a full-text version of this article with your friends and colleagues. Authors Fuad Alrowaishdi 1 , Sophie Colomb, Bernard Guillot, Nadia Raison-Peyron. The differential diagnosis was challenging due to concomitant contact sensitization with these agents. Clipboard, Search History, and several other advanced features are temporarily unavailable. Allergic Contact Cheilitis From a Variety of Lip Balm Ingredients Linghong Linda Zhou and Melanie Pratt Journal of Cutaneous Medicine and Surgery 2017 22 : 3 , 333-335 Allergic contact cheilitis is an allergic reaction to lip products, dental materials, toothpaste, or medication. Lip dryness due to internal diseases is less common. Contact cheilitis from bisabolol and polyvinylpyrrolidone/hexadecene copolymer in lipstick. Please enable it to take advantage of the complete set of features! View the article PDF and any associated supplements and figures for a period of 48 hours. No evidence of contact sensitization to acyclovir in acute dermatitis of the lips following local application of Zovirax cream. CONTACT CHEILITIS is an inflammatory condition of the lips that can manifest as itching, burning, dryness, erythema, fissuring, crusting, and edema. Patch tests were positive to Zovirax cream, propylene glycol, the patient's favourite lipstick and propyl gallate. In this case, it was caused by chemical substances contained in the lipstick worn by the patient. 2013 Nov;69(5):318-9. doi: 10.1111/cod.12108. Inflammation of the lips is called cheilitis and can be caused by irritation or allergic reactions. The prototypical vignette is a wife with allergic contact cheilitis driven by an allergy to her husband’s aftershave. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. Author information: (1)1 Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada. | Zeynep Topkarcı, MD. Allergic contact cheilitis describes a not uncommon inflammatory reaction of the lips. Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. An itchy sensation on your lips can happen suddenly and be quite uncomfortable. Contact Cheilitis is caused by exposure to irritating chemicals, which can be found in food and skin care products. Allergic Contact Cheilitis: A delayed-type hypersensitivity reaction to allergens that come in contact with the lips can cause inflammation of the lips. Allergic contact cheilitis is more common in women than men. Contact Dermatitis 1995; 33:365. A 29‐year‐old Turkish woman with allergic contact cheilitis from a lipstick was misdiagnosed as herpes labialis and subsequently worsened with the application of Zovirax® cream. A possible cause of cheilitis is contact allergy. COVID-19 is an emerging, rapidly evolving situation. 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